Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H
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![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.researchgate.net/publication/5503612/figure/fig1/AS:280211393400832@1443819010059/Disruption-of-Mtmr13-A-A-representation-of-the-manner-in-which-Mtmr13-is-disrupted.png)
Disruption of Mtmr13 . ( A ) A representation of the manner in
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Soluble neuregulin-1 modulates disease pathogenesis in rodent
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.biorxiv.org/content/biorxiv/early/2022/01/22/2022.01.20.477077/F3.large.jpg)
Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered
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The role of neuregulin-1 in the response to nerve injury
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.researchgate.net/publication/309617961/figure/fig2/AS:432411382161417@1480106315440/Figure-EV5-Bioclinical-analysis-in-Mtmr2-A-A-mice-treated-with-Niaspan-for-2-months-160.png)
Figure EV5. Bioclinical analysis in Mtmr2 À/À mice treated with
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.frontiersin.org/files/Articles/662474/fnagi-13-662474-HTML-r1/image_m/fnagi-13-662474-g002.jpg)
Frontiers Neuregulins in Neurodegenerative Diseases
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.researchgate.net/publication/353930631/figure/fig1/AS:1057419056652288@1629119757079/Schematic-overview-of-the-intracellular-trafficking-processes-in-a-neuron-of-the-PNS_Q320.jpg)
Schematic overview of the intracellular trafficking processes in a
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.researchgate.net/publication/223970447/figure/fig5/AS:279166688743434@1443569933203/Enhanced-AKT-activity-and-unaltered-expression-levels-of-Dlg1-and-Par-3AImmunostaining.png)
Enhanced AKT activity and unaltered expression levels of Dlg1 and
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.researchgate.net/publication/301571336/figure/fig1/AS:359944844005377@1462828946431/Loss-of-individual-Akt-isoforms-in-vivo-does-not-affect-PNS-myelination-A-Western-blot.png)
Loss of individual Akt isoforms in vivo does not affect PNS
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://d3i71xaburhd42.cloudfront.net/c91b6f71933d99373843d3bf3fa8a8ea9793a6e0/2-Figure1-1.png)
The first Japanese case of Charcot–Marie–Tooth disease type 4H
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://www.researchgate.net/publication/289501300/figure/fig4/AS:962711101923344@1606539621521/Proposed-model-of-dysregulated-ErbB-receptor-trafficking-and-signaling-in-demyelinating.gif)
Proposed model of dysregulated ErbB receptor trafficking and
![Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H](https://d3i71xaburhd42.cloudfront.net/7e8a6204c57d59173ee660f2615c6c3334938612/9-Figure5-1.png)
PDF] Myelin is dependent on the Charcot–Marie–Tooth Type 4H
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Full article: Aberrant Neuregulin 1/ErbB Signaling in Charcot
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