Glutaminyl Cyclase, Diseases, and Development of Glutaminyl

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Increased glutaminyl cyclase activity in brains of Alzheimer's disease individuals - Gunn - 2021 - Journal of Neurochemistry - Wiley Online Library

Glutaminyl Cyclase, Diseases, and Development of Glutaminyl Cyclase Inhibitors

Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology

Upregulation of Glutaminyl Cyclase Contributes to ERS-Induced Apoptosis in PC12 Cells

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IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes

is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM.Glutaminyl Cyclase Inhibitor 1 is compound 23[1].[1]. Li M, et al. Synthesis and

Glutaminyl Cyclase Inhibitor 1

A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies

Glutaminyl cyclase (QC) converts N-aminoterminal glutamate residue to

Therapeutic potential of glutaminyl cyclases: Current status and emerging trends - ScienceDirect

Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes - ScienceDirect

Full article: A patent review of glutaminyl cyclase inhibitors (2004–present)

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A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies

Glutaminyl Cyclase, Diseases, and Development of Glutaminyl Cyclase Inhibitors

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